Auer Rod-Like Inclusions in B-Cell Prolymphocytic Leukemia

Myeloma Cells with Auer Rod-like Inclusions

The presented image showings heavily granulated myeloma cells, some with Auer rod-like inclusions. Auer rod-like inclusions in myeloma are composed of crystallized lysosomal enzyme depositions. They are distinguished from intracytoplasmic immunoglobulin crystals. The factors that predispose to Auer rod-like inclusions in myeloma are unknown; however, in all reported cases paraprotein was of the...

Multiple myeloma with Auer-rod-like inclusions.

A64 year old woman complaining of a long-lasting bone pain in the lumbar region was admitted to our Institute. Routine laboratory examination on admission disclosed: Hb 10.1 g/dL; RBC 3.3531012/L, WBC 5.93109/L, PTL 203109/L. Differential blood count showed occasional plasma cells with atypical features in the peripheral blood. Serum electrophoresis demonstrated a peak in the g region (56%) com...

Auer rod-like inclusions in κ light chain myeloma.

A 56-year-old woman with a history of dyslipidemia and hepatic steatosis presented with weight loss and progressive proteinuria. The presenting blood count was normal: white blood cells, 10.9 3 10/L; hemoglobin, 15.5 g/dL; platelet count, 236 3 10/L. No significant rouleaux formations were present on the peripheral blood smear. Calcium (9.28 mg/dL), blood urea nitrogen/creatinine (15/0.78 mg/dL...

Auer Rod-Like Inclusions in Reactive Plasma Cells in a Case of Acute Myeloid Leukemia

p53 abnormalities in B-cell prolymphocytic leukemia.

B-cell prolymphocytic leukemia (B-PLL) is an aggressive disorder of mature B cells with distinct clinical and pathologic features. To determine the incidence of abnormalities of p53, we analyzed 19 cases of B-PLL by DNA blot to assess loss of heterozygosity (LOH) at 17p13.3, by immunocytochemistry to assess p53 expression, and by direct DNA sequencing of polymerase chain reaction-amplified exon...